Publications by Leidecker Laboratories
Browse our recent publications sorted by publication year.
Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer
Ratz L, Brambillasca C, Bartke L, Huetzen M, Goergens J, Leidecker O, Jachimowicz R, van de Ven M, Proost N, Siteur B, de Korte-Grimmerink R, Bouwman P, M. Pulver E; de Bruijn R, Isensee J, Hucho T, Pandey G, van Lohuizen M, Mallmann P, Reinhardt HC, Jonkers J, Puppe J
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PMID:35715861
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Journal:Breast Cancer Research
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Date:27. Juni 2022
Structural insight into SUMO chain recognition and manipulation by the ubiquitin ligase RNF4
Xu Y, Plechanovová A, Simpson P, Marchant J, Leidecker O, Kraatz S, Hay RT, Matthews SJ
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PMID:24969970
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Journal:Nature Communications
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Date:27. Juni 2014
Processing of protein ADP-ribosylation by Nudix hydrolases
Palazzo L, Thomas B, Jemth AS, Colby T, Leidecker O, Feijs KL, Zaja R, Loseva O, Puigvert JC, Matic I, Helleday T, Ahel I
Identification of a class of protein ADP-ribosylating sirtuins in microbial pathogens
Rack JG, Morra R, Barkauskaite E, Kraehenbuehl R, Ariza A, Qu Y, Ortmayer M, Leidecker O, Cameron DR, Matic I, Peleg AY, Leys D, Traven A, Ahel I
The NEDD8 cycle controlled by NEDP1 upon DNA damage is a regulatory module of the HSP70 ATPase activity
Bailly AP, Perrin A, Marina SM, Maghames C, Leidecker O, Trauchessec H, Gartner A and Xirodimas DP
SUMOylation regulates Lem2 function in centromere clustering and silencing
Strachan J, Leidecker O, Spanos C, Le Coz C, Chapman E, Arsenijevic A, Zang H, Zhao N, Spoel S, Bayne EH
The ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditions
Leidecker O, Matic I, Mahata B, Pion E & Xirodimas DP
Serine is a new target residue for endogenous ADP-ribosylation on histones
Leidecker O*, Bonfiglio JJ*, Colby T, Zhang Q, Atanassov I, Zaja R, Palazzo L, Stockum A, Ahel I, Matic I
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PMID:27723750
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Journal:Nature Chemical Biology
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Date:10. Oktober 2016
Serine is the major residues for ADP-ribosylation upon DNA damage
Palazzo L*, Leidecker O*, Prokhorova E*, Dauben H, Matic I and Ahel I
An HPF1/PARP1-Based Chemical Biology Strategy for Exploring ADP-Ribosylation
1. Bonfiglio JJ*, Leidecker O*, Dauben H*, Longarini EJ*, Colby T, San Segundo-Acosta P and Matic I