Newest Publications

Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age

Molière A, Park JYC, Goyala A, Vayndorf EM, Zhang B, Hsiung KC, Jung Y, Kwon S, Statzer C, Meyer D, Nguyen R, Chadwick J, Thompson MA, Schumacher B, Lee SV, Essmann CL, MacArthur MR, Kaeberlein M, David D, Gems D, Ewald CY.
Geroscience. 2024 Jun 20.
https://doi.org/10.1007/s11357-024-01232-x. Online ahead of print.
PMID: 38900346

Distinct DNA repair mechanisms prevent formaldehyde toxicity during development, reproduction and aging

Rieckher M, Gallrein C, Alquezar-Artieda N, Bourached-Silva N, Vaddavalli PL, Mares D, Backhaus M, Blindauer T, Greger K, Wiesner E, Pontel LB, Schumacher B.
Nucleic Acids Res. 2024 Jun 19:gkae519.
https://doi.org/10.1093/nar/gkae519. Online ahead of print.
PMID: 38894680

Transcription stress at telomeres leads to cytosolic DNA release and paracrine senescence

Siametis A, Stratigi K, Giamaki D, Chatzinikolaou G, Akalestou-Clocher A, Goulielmaki E, Luke B, Schumacher B, Garinis GA.
Nat Commun. 2024 May 14;15(1):4061.
https://doi.org/10.1038/s41467-024-48443-6.

Aging clocks based on accumulating stochastic variation.

Meyer DH, Schumacher B.
Nat Aging. 2024 May 9. doi: 10.1038/s43587-024-00619-x. Online ahead of print.
PMID: 38724736

DNA repair deficiencies and neurodegeneration.

Ropert B, Gallrein C, Schumacher B.
DNA Repair (Amst). 2024 Apr 16;138:103679. doi: 10.1016/j.dnarep.2024.103679. Online ahead of print.
PMID: 38640601