Schumacher Lab Publications

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Genome Instability and DNA Repair in Somatic and Reproductive Aging.

Panier S, Wang S, Schumacher B.
Genome Instability and DNA Repair in Somatic and Reproductive Aging.
Annu Rev Pathol. 2024 Jan 24;19:261-290. doi: 10.1146/annurev-pathmechdis-051122-093128. Epub 2023 Oct 13. PMID: 37832947

baz-2 enhances systemic proteostasis in vivo by regulating acetylcholine metabolism.

Gallrein C, Williams AB, Meyer DH, Messling JE, Garcia A, Schumacher B
baz-2 enhances systemic proteostasis in vivo by regulating acetylcholine metabolism.
Cell Rep. 2023 Dec 26;42(12):113577. doi: 10.1016/j.celrep.2023.113577. Epub 2023 Dec 14.
PMID: 38100354

Chronic kidney disease promotes ageing in a multiorgan disease network

Benzing T, Schumacher B.
Nat Rev Nephrol. 2023 May 26.
doi: 10.1038/s41581-023-00729-6. Online ahead of print.

Mitigating age-related somatic mutation burden

Vijg J, Schumacher B, Abakir A, Antonov M, Bradley C, Cagan A, Church G, Gladyshev VN, Gorbunova V, Maslov AY, Reik W, Sharifi S, Suh Y, Walsh K.
Trends Mol Med. 2023 Apr 28:S1471-4914(23)00072-2.
doi: 10.1016/j.molmed.2023.04.002. Online ahead of print.

The DREAM complex functions as conserved master regulator of somatic DNA repair capacities.

Bujarrabal A, Sendtner G, Meyer DH, Chatzinikolaou G, Stratigi G, Garinis G, Schumacher B.
Nat Struct Mol Biol. 2023 Mar 23.
https://doi.org/10.1038/s41594-023-00942-8

Short-Term UVB Irradiation Leads to Persistent DNA Damage in Limbal Epithelial Stem Cells, Partially Reversed by DNA Repairing Enzymes.

Volatier T, Schumacher B, Meshko B, Hadrian K, Cursiefen C, Notara M.
Biology (Basel). 2023 Feb 7;12(2):265.
https://doi.org/10.3390/biology12020265

The novel role of lymphatic vessels in the pathogenesis of ocular diseases.

Clahsen T, Hadrian K, Notara M, Schlereth SL, Howaldt A, Prokosch V, Volatier T, Hos D, Schroedl F, Kaser-Eichberger A, Heindl LM, Steven P, Bosch JJ, Steinkasserer A, Rokohl AC, Liu H, Mestanoglu M, Kashkar H, Schumacher B, Kiefer F, Schulte-Merker S, Matthaei M, Hou Y, Fassbender S, Jantsch J, Zhang W, Enders P, Bachmann B, Bock F, Cursiefen C.
Prog Retin Eye Res. 2023 Feb 7:101157.
https://doi.org/10.1016/j.preteyeres.2022.101157

Perinatal Obesity Sensitizes for Premature Kidney Aging Signaling
Selle J, Bohl K, Höpker K, Wilke R, Dinger K, Kasper P, Abend B, Schermer B, Müller R, Kurschat C, Nüsken K, Nüsken E, Meyer D, Savai Pullamsetti S, Schumacher B, Dötsch J, Alejandre Alcazar M,
Int. J. Mol. Sci. 2023, 24(3), 2508;
https://doi.org/10.3390/ijms24032508

Inheritance of paternal DNA damage by histone-mediated repair restriction.

Wang, S., Meyer, D.H. & Schumacher, B.
Nature
2023 Jan;613(7943):365-374.
https://doi.org/10.1038/s41586-022-05544-w

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