Schumacher Lab Publications

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Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity.

Schwer B, Schumacher B, Lombard DB, Xiao C, Kurtev MV, Gao J, Schneider JI, Chai H, Bronson RT, Tsai LH, Deng CX, Alt FW.
Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity.
Proc Natl Acad Sci U S A. 2010 Nov 22.

Next Generation Sequencing of miRNAs Strategies, Resources and Methods.

Motameny S, Wolters S, Nürnberg P, Schumacher B.
Next Generation Sequencing of miRNAs Strategies, Resources and Methods.
Genes. 2010; 1(1):70-84.

Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development.

Lans H, Marteijn JA, Schumacher B, Hoeijmakers JH, Jansen G, Vermeulen W.
Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development.
PLoS Genet. 2010 May 6;6:e1000941.

Transcription-blocking DNA damage in aging: a mechanism for hormesis.

Schumacher B
Transcription-blocking DNA damage in aging: a mechanism for hormesis.
Bioessays. 2009 Dec;31(12):1347-56.

Transcription-blocking DNA damage in aging and longevity.

Garinis GA, Schumacher B
Transcription-blocking DNA damage in aging and longevity.
Cell Cycle. 2009 Jul 20;8(14).

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.

Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LHF, van der Horst GTJ, Brüning JC, Niessen CM, Hoeijmakers JHJ and Schumacher B
Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.
Nature Cell Biol. 2009 May;11(5):604-15.

Sealing the gap between nuclear DNA damage and longevity.

Schumacher B, Hoeijmakers JH, Garinis GA
Sealing the gap between nuclear DNA damage and longevity.
Cell Endocrinol. 2009 Feb 5;299(1):112-7. Epub 2008 Nov 5.

Delayed and accelerated aging share common longevity assurance mechanisms.

Schumacher B, van der Pluijm I, Moorhouse MJ, Rasile Robinson A, Suh Y, Breit TM, van Steeg H, Niedernhofer LJ, van Ijcken W, Bartke A, Spindler SR, Hoeijmakers JHJ, van der Horst GTJ and Garinis GA
Delayed and accelerated aging share common longevity assurance mechanisms.
PLoS Genet. 2008 Aug 15;4(8):e1000161.

Transcriptional profiling in C. elegans cep-1/p53 dependent apoptosis as a primordial function of p53 like genes.

Greiss S#, Schumacher B#, Grandien K, Rothblatt J and Gartner A
Transcriptional profiling in C. elegans cep-1/p53 dependent apoptosis as a primordial function of p53 like genes.
BMC Genomics. 2008 Jul 15;9(1):334.

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