Schumacher Lab Publications

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DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.

Ermolaeva MA, Segref A, Dakhovnik A, Ou HL, Schneider JI, Utermöhlen O, Hoppe T, Schumacher B.
DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.
Nature. 2013 Sep 19;501(7467):416-20. doi: 10.1038/nature12452.

Transcriptional profiling reveals progeroid Ercc1-/Δ mice as a model system for glomerular ageing.

Schermer B, Bartels V, Frommolt P, Habermann B, Braun F, Schultze JL, Roodbergen M, Hoeijmakers JH, Schumacher B, Nürnberg P, Dollé ME, Benzing T, Müller RU,
Kurschat CE.
Transcriptional profiling reveals progeroid Ercc1-/Δ mice as a model system for glomerular ageing.
BMC Genomics. 2013 Aug 16;14:559. doi: 10.1186/1471-2164-14-559.

Genome maintenance and transcription integrity in aging and disease.

Wolters S, Schumacher B
Genome maintenance and transcription integrity in aging and disease.
Front Genet. 2013;4:19. doi: 10.3389/fgene.2013.00019. Epub 2013 Feb 25

DNA-Reparatur und Alterung

Schumacher B
DNA-Reparatur und Alterung
Medgen. 2012; 24: 289-296

AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repressp53-driven apoptosis.

Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos ML, Thomas RK, Lowery D, Roels F, Fischer M, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Ulrich Müller R, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema RH, Yaffe MB, Schermer B, Christian Reinhardt H, Benzing T
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repressp53-driven apoptosis.
EMBO J. 2012 Aug 21.

The p53 network: Cellular and systemic DNA damage responses in aging and cancer.

Reinhardt HC, Schumacher B
The p53 network: Cellular and systemic DNA damage responses in aging and cancer.
Trends Genet. 2012 Mar;28(3):128-36.

Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity.

Schwer B, Schumacher B, Lombard DB, Xiao C, Kurtev MV, Gao J, Schneider JI, Chai H, Bronson RT, Tsai LH, Deng CX, Alt FW.
Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity.
Proc Natl Acad Sci U S A. 2010 Nov 22.

Next Generation Sequencing of miRNAs Strategies, Resources and Methods.

Motameny S, Wolters S, Nürnberg P, Schumacher B.
Next Generation Sequencing of miRNAs Strategies, Resources and Methods.
Genes. 2010; 1(1):70-84.

Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development.

Lans H, Marteijn JA, Schumacher B, Hoeijmakers JH, Jansen G, Vermeulen W.
Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development.
PLoS Genet. 2010 May 6;6:e1000941.

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