Schumacher Lab Publications

Schumacher B
Transcription-blocking DNA damage in aging: a mechanism for hormesis.
Bioessays. 2009 Dec;31(12):1347-56.

Garinis GA, Schumacher B
Transcription-blocking DNA damage in aging and longevity.
Cell Cycle. 2009 Jul 20;8(14).

Garinis GA, Uittenboogaard LM, Stachelscheid H, Fousteri M, van Ijcken W, Breit TM, van Steeg H, Mullenders LHF, van der Horst GTJ, Brüning JC, Niessen CM, Hoeijmakers JHJ and Schumacher B
Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity.
Nature Cell Biol. 2009 May;11(5):604-15.

Schumacher B, Hoeijmakers JH, Garinis GA
Sealing the gap between nuclear DNA damage and longevity.
Cell Endocrinol. 2009 Feb 5;299(1):112-7. Epub 2008 Nov 5.

Schumacher B, van der Pluijm I, Moorhouse MJ, Rasile Robinson A, Suh Y, Breit TM, van Steeg H, Niedernhofer LJ, van Ijcken W, Bartke A, Spindler SR, Hoeijmakers JHJ, van der Horst GTJ and Garinis GA
Delayed and accelerated aging share common longevity assurance mechanisms.
PLoS Genet. 2008 Aug 15;4(8):e1000161.

Greiss S#, Schumacher B#, Grandien K, Rothblatt J and Gartner A
Transcriptional profiling in C. elegans cep-1/p53 dependent apoptosis as a primordial function of p53 like genes.
BMC Genomics. 2008 Jul 15;9(1):334.

Schumacher B, Garinis G, Hoeijmakers J
Age to survive: DNA damage and aging.
Trends Genet. 2008 Feb;24(2):77-85

Garinis G, Patil C, Schumacher B
"The molecular basis of aging": the Boehringer Ingelheim Fonds 95th International Titisee Conference.
Mech Ageing Dev. 2007 Jul-Aug;128(7-8):469-75.

Schumacher B & Gartner A
Translational regulation of p53 as a potential tumor therapy target.
Future Oncology, 2006;2(1):145-153.