Schumacher Lab Publications

Hormesis running hot and cold.

Bujarrabal A, Schumacher B.
Hormesis running hot and cold.
Cell Cycle. 2016 Sep 29:0. [Epub ahead of print]

E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis.

Ackermann L, Schell M, Pokrzywa W, Kevei E, Gartner B, Schumacher B#, Hoppe T#.
E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis.
Nat Struct Mol Biol. 2016 Sep 26. doi: 10.1038/nsmb.3296. [Epub ahead of print]
(#co-corresponding authors)

Targeting transcription-coupled nucleotide excision repair overcomes resistance in chronic lymphocytic leukemia.

Lohmann G, Vasyutina E, Bloehdorn J, Reinart N, Schneider JI, Babu V, Knittel G, Crispatzu G, Mayer P, Prinz C, Biersack B, Efremov DG, Chessa L, Herling CD, Stilgenbauer S, Hallek M, Schobert R, Reinhardt HC, Schumacher B, Herling M.
Targeting transcription-coupled nucleotide excision repair overcomes resistance in chronic lymphocytic leukemia.
Leukemia. 2017 May;31(5):1177-1186. doi: 10.1038/leu.2016.294. Epub 2016 Oct 24.

The tumour suppressor CYLD regulates the p53 DNA damage response.

Fernández-Majada V, Welz PS, Ermolaeva MA, Schell M, Adam A, Dietlein F, Komander D, Büttner R, Thomas RK, Schumacher B, Pasparakis M.
The tumour suppressor CYLD regulates the p53 DNA damage response.
Nat Commun. 2016 Aug 26;7:12508. doi: 10.1038/ncomms12508.

Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a TP53 Context-specific Manner

Jokic M, Vlasic I, Rinneburger M, Klumper N, Spiro J, Vogel W, Offermann A, Kuempers C, Fritz C, Schmitt A, Riabinska A, Wittersheim M, Michels S, Ozretic L,
Florin A, Welcker D, Akyuz MD, Nowak M, Erkel M, Wolf J, Buttner R, Schumacher B, Thomale J, Persigehl T, Maintz D, Perner S, Reinhardt HC
Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a TP53 Context-specific Manner
Mol Cancer Res. 2016 Aug 11. pii: molcanres.0094.2016. [Epub ahead of print]

p53 in the DNA-Damage-Repair Process.

Willams AB, Schumacher B
p53 in the DNA-Damage-Repair Process.
Cold Spring Harb Perspect Med. 2016 Apr 5. pii: a026070. doi: 10.1101/cshperspect.a026070. [Epub ahead of print]

Genome Instability: Linking Aging and Brain Degeneration.

Barzilai A, Schumacher B, Shiloh, Y
Genome Instability: Linking Aging and Brain Degeneration.
Mech Ageing Dev. 2016 Mar 31. pii: S0047-6374(16)30039-2. doi: 10.1016/j.mad.2016.03.011. [Epub ahead of print]

A C. elegans homolog for the UV-hypersensitivity syndrome disease gene UVSSA.

Babu V, Schumacher B
A C. elegans homolog for the UV-hypersensitivity syndrome disease gene UVSSA.
DNA Repair (Amst). 2016 Mar 25;41:8-15. doi: 10.1016/j.dnarep.2016.03.008. [Epub ahead of print]