Schumacher Lab Publications

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DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage.

Mueller MM*, Castells-Roca L*, Babu V, Ermolaeva MA, Müller RU, Frommolt P, Williams AB, Greiss S, Schneider JI, Benzing T, Schermer B, Schumacher B.
DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage.
Nat Cell Biol. 2014 Nov 24. doi: 10.1038/ncb3071. (*equal contribution)

Proteome analysis in the assessment of ageing.

Nkuipou-Kenfack E, Koeck T, Mischak H, Pich A, Schanstra JP, Zürbig P, Schumacher B.
Proteome analysis in the assessment of ageing.
Ageing Res Rev. 2014 Sep 22. pii: S1568-1637(14)00105-6.
doi:10.1016/j.arr.2014.09.002.

Insights from the worm: The C. elegans model for innate immunity.

Ermolaeva MA, Schumacher B.
Insights from the worm: The C. elegans model for innate immunity. Semin Immunol (2014)

Impact of genomic damage and ageing on stem cell function.

Behrens A, van Deursen JM, Rudolph KL, Schumacher B.
Impact of genomic damage and ageing on stem cell function.
Nat Cell Biol. 2014 Feb 28;16(3):201-7. doi: 10.1038/ncb2928.

Systemic DNA damage responses: organismal adaptations to genome instability.

Ermolaeva MA, Schumacher B.
Systemic DNA damage responses: organismal adaptations to genome instability.
Trends Genet. 2014 Mar;30(3):95-102. doi: 10.1016/j.tig.2013.12.001. Epub 2014 Jan 15.

Loss of Caenorhabditis elegans BRCA1 Promotes Genome Stability During Replication in smc-5 Mutants.

Wolters S, Ermolaeva MA, Bickel JS, Fingerhut JM, Khanikar J, Chan RC, Schumacher B.
Loss of Caenorhabditis elegans BRCA1 Promotes Genome Stability During Replication in smc-5 Mutants.
Genetics. 2014 Apr;196(4):985-99. doi: 10.1534/genetics.113.158295. Epub 2014 Jan 14.

The innate immune system as mediator of systemic DNA damage responses.

Ermolaeva M, Schumacher B.
The innate immune system as mediator of systemic DNA damage responses.
Communicative & Integrative Biology 2013; 6:e26926; doi:10.4161/cib.26926

DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.

Ermolaeva MA, Segref A, Dakhovnik A, Ou HL, Schneider JI, Utermöhlen O, Hoppe T, Schumacher B.
DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.
Nature. 2013 Sep 19;501(7467):416-20. doi: 10.1038/nature12452.

Transcriptional profiling reveals progeroid Ercc1-/Δ mice as a model system for glomerular ageing.

Schermer B, Bartels V, Frommolt P, Habermann B, Braun F, Schultze JL, Roodbergen M, Hoeijmakers JH, Schumacher B, Nürnberg P, Dollé ME, Benzing T, Müller RU,
Kurschat CE.
Transcriptional profiling reveals progeroid Ercc1-/Δ mice as a model system for glomerular ageing.
BMC Genomics. 2013 Aug 16;14:559. doi: 10.1186/1471-2164-14-559.

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