Schumacher Lab Publications

Mitochondrial stress prevents C. elegans germline apoptosis via BRCA1/BARD1 tumor suppressor genes independently from its pro-longevity effect.

Torgovnick A, Schiavi A, Shaik A, Kassahun H, Maglioni S, Rea SL, Johnson TE, Reinhardt HC, Honnen S, Schumacher B, Nilsen H, Ventura N.
Mitochondrial stress prevents C. elegans germline apoptosis via BRCA1/BARD1 tumor suppressor genes independently from its pro-longevity effect.
EMBO Rep. 2018, e45856. doi: 10.15252/embr.201845856. Epub 2018 Oct 26.

The Cdkn1aSUPER mouse as a novel tool to study p53-mediated tumor suppression.

Torgovnick A#, Heger JM, Liaki V, Isensee J, Schmitt A, Knittel G, Riabinska A, Beleggia F, Laurien L, Leeser U, Jüngst C, Siedek F, Vogel W, Klümper N, Nolte H, Wittersheim M, Tharun L, Castiglione R, Krüger M, Schauss A, Perner S, Pasparakis M, Büttner R, Persigehl T, Hucho T, Herter-Sprie GS, Schumacher B#, Reinhardt HC#.
The Cdkn1aSUPER mouse as a novel tool to study p53-mediated tumor suppression.
Cell Rep. 2018 Oct 23;25(4), 1027-1039. doi: 10.1016/j.celrep.2018.09.079
(#co-corresponding authors)

Maintenance of Proteostasis by P Body-Mediated Regulation of eIF4E Availability during Aging in Caenorhabditis elegans.

Rieckher M, Markaki M, Princz A, Schumacher B, Tavernarakis N.
Maintenance of Proteostasis by P Body-Mediated Regulation of eIF4E Availability during Aging in Caenorhabditis elegans.
Cell Rep. 2018 Oct 2;25(1):199-211.e6. doi: 10.1016/j.celrep.2018.09.009.

Nematoda: The Caenorhabditis elegans Model for Innate Immunity Interactions Between Worms and Pathogens, and Their Responses to Immunogenic Damage

Williams AB, Schumacher B.
Nematoda: The Caenorhabditis elegans Model for Innate Immunity Interactions Between Worms and Pathogens, and Their Responses to Immunogenic Damage
Advances in Comparative Immunology, 2018

MPK-1/ERK pathway regulates DNA damage response during development through DAF-16/FOXO

Bianco J, Schumacher B.
MPK-1/ERK pathway regulates DNA damage response during development through DAF-16/FOXO
Nucleic Acids Res. 2018. doi:10.1093/nar/gky404

Nucleotide excision repair as a targetable vulnerability in leukemia

Lohmann G, Schumacher B, Herling M
Nucleotide excision repair as a targetable vulnerability in leukemia
Oncotarget. 2017 Dec 6;8(70):114420-114421. doi: 10.18632/oncotarget.22998. eCollection 2017 Dec 29.

Demonstrating improved multiple transport-mean-free-path imaging capabilities of light sheet microscopy in the quantification of fluorescence dynamics

Rieckher M, Psycharakis S, Ancora D, Liapis E, Zacharopoulos A, Ripoll J, Tavernarakis N, Zacharakis G
Demonstrating improved multiple transport-mean-free-path imaging capabilities of light sheet microscopy in the quantification of fluorescence dynamics
Biotechnol J. 2017 Nov 23. doi: 10.1002/biot.201700419. [Epub ahead of print]

DNA damage responses and p53 in the aging process

Ou HL, Schumacher B
DNA damage responses and p53 in the aging process
Blood 2017 :blood-2017-07-746396; doi: 10.1182/blood-2017-07-746396

Omics Approaches for Identifyiung Physiological Adaptations to Genome Instability in Aging

Edifizi D, Schumacher B
Omics Approaches for Identifyiung Physiological Adaptations to Genome Instability in Aging
Int. J. Mol. Sci. 2017, 18(11), 2329; doi: 10.3390/ijms18112329