Schumacher Lab Publications

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Evaluating DNA damage response through immunofluorescence staining of primordial germ cells in Caenorhabditis elegans L1 Larva.

Ou HL, Schumacher B.
Evaluating DNA damage response through immunofluorescence staining of primordial germ cells in Caenorhabditis elegans L1 Larva.
STAR Protoc. 2021 Apr 5;2(2):100441. eCollection 2021 Jun 18.
https://doi.org/10.1016/j.xpro.2021.100441

The Aging Skin: From Basic Mechanisms to Clinical Applications.

Schumacher B, Krieg TM.
The Aging Skin: From Basic Mechanisms to Clinical Applications.
J Invest Dermatol. 2021 Apr;141(4S):949-950.
https://doi.org/10.1016/j.jid.2020.12.002.

BiT age: A transcriptome-based aging clock near the theoretical limit of accurarcy.

Meyer DH, Schumacher B.
BiT age: A transcriptome-based aging clock near the theoretical limit of accurarcy.
Aging Cell 2021;
https://doi.org/10.1111/acel.13320

Principles of the Molecular and Cellular Mechanisms of Aging.

da Silva PFL, Schumacher B.
Principles of the Molecular and Cellular Mechanisms of Aging.
J Invest Dermatol. 2021 Jan 28:S0022-202X(20)32362-2.
https://doi.org/10.1016/j-jid.2020.11.018

DNA Dmaged Induced Cell Death in Oocytes

Gebel J, Tuppi M, Sänger N, Schumacher B, Dötsch V.
DNA Dmaged Induced Cell Death in Oocytes
Molecules. 2020 Dec 3;25(23):E5714.
https://dio.org/10.3390/molecules25235714

H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage.

Wang S, Meyer DH, Schumacher B.
H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage.
Nat Struct Mol Biol 2020 Dec;27(12):1165-1177. https://doi.org/10.1038/s41592-020-00513-1

A C. elegans model for neurodegeneration in Cockayne syndrome

Lopes AFC, Bozek K, Herholz M, Trifunovic A, Rieckher M#, Schumacher B#.
A C. elegans model for neurodegeneration in Cockayne syndrome
Nucleic Acids Research, 2020 Nov 4;48(19):10973-10985,
https://doi.org/10.1093/nar/gkaa795
(#co-corresponding authors)

A transcriptome based aging clock near the theoretical limit of accuracy.

Meyer DH, Schumacher B.
A transcriptome based aging clock near the theoretical limit of accuracy.
BioRxiv 2020; doi: https://doi.org/10.1101/2020.05.29.123430

Endogenous formaldehyde scavenges cellular glutathione resulting in cytotoxic redox disruption

Umansky C*, Morellato A*, Scheidegger M*, Rieckher M*, Martinefski MR, Fernandez GA, Kolesnikova K, Vesting AJ, Karakasilioti I, Reingruber H, Wei Y, He R, Bollini M, Monge ME, Schumacher B, Pontel LB.
Endogenous formaldehyde scavenges cellular glutathione resulting in cytotoxic redox disruption
BioRxiv 2020; dio https://doi.org/10.1101/2020.05.14.090738 (*equal contribution)

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