Schumacher Lab Publications

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Principles of the Molecular and Cellular Mechanisms of Aging.

da Silva PFL, Schumacher B.
Principles of the Molecular and Cellular Mechanisms of Aging.
J Invest Dermatol. 2021 Jan 28:S0022-202X(20)32362-2.
https://doi.org/10.1016/j-jid.2020.11.018

DNA Dmaged Induced Cell Death in Oocytes

Gebel J, Tuppi M, Sänger N, Schumacher B, Dötsch V.
DNA Dmaged Induced Cell Death in Oocytes
Molecules. 2020 Dec 3;25(23):E5714.
https://dio.org/10.3390/molecules25235714

H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage.

Wang S, Meyer DH, Schumacher B.
H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage.
Nat Struct Mol Biol 2020 Dec;27(12):1165-1177. https://doi.org/10.1038/s41592-020-00513-1

A C. elegans model for neurodegeneration in Cockayne syndrome

Lopes AFC, Bozek K, Herholz M, Trifunovic A, Rieckher M#, Schumacher B#.
A C. elegans model for neurodegeneration in Cockayne syndrome
Nucleic Acids Research, 2020 Nov 4;48(19):10973-10985,
https://doi.org/10.1093/nar/gkaa795
(#co-corresponding authors)

A transcriptome based aging clock near the theoretical limit of accuracy.

Meyer DH, Schumacher B.
A transcriptome based aging clock near the theoretical limit of accuracy.
BioRxiv 2020; doi: https://doi.org/10.1101/2020.05.29.123430

Endogenous formaldehyde scavenges cellular glutathione resulting in cytotoxic redox disruption

Umansky C*, Morellato A*, Scheidegger M*, Rieckher M*, Martinefski MR, Fernandez GA, Kolesnikova K, Vesting AJ, Karakasilioti I, Reingruber H, Wei Y, He R, Bollini M, Monge ME, Schumacher B, Pontel LB.
Endogenous formaldehyde scavenges cellular glutathione resulting in cytotoxic redox disruption
BioRxiv 2020; dio https://doi.org/10.1101/2020.05.14.090738 (*equal contribution)

ATM-mediated DNA damage response in macrophages primes phagocytosis and immune checkpoint regulation.

Bansal A, Neuhaus R, Izquierdo-Alvarez E, Vorholt D, Feldkötter H, Nolte H, Lohneis P, Büttner R, Krüger M, Pallasch CP, Schumacher B.
ATM-mediated DNA damage response in macrophages primes phagocytosis and immune checkpoint regulation.
BioRxiv 2020; doi: https://doi.org/10.1101/2020.03.14.987438

DNA Damage Response and Metabolic Reprogramming in Health and Disease.

Chatzidoukaki O, Goulielmaki E, Schumacher B, Garinis GA.
DNA Damage Response and Metabolic Reprogramming in Health and Disease.
Trends Genet. 2020 Jul 16:S0168-9525(20)30166-9-
https://doi.org/10.1016/j.tig.2020.06.018.

DNA damage responses in ageing.

da Silva PFL, Schumacher B.
DNA damage responses in ageing.
Open Biol. 2019 Nov 29;9(11):190168. doi: 10.1098/rsob.190168. Epub 2019 Nov 20.

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